Utilizing supervised machine learning algorithms to develop a surveillance and response system based on symptoms of diarrhoea, contingent on the Support Vector Machine (SVM) to predict the probable disease using labelled data.Diarrhoea is amongst the top ten diseases which kill.A prototype system is developed based on the SVM algorithm.The prototyp
Hepatic lipase (HL) and lipoprotein lipase (LPL) are evolutionarily related enzymes that are essential for normal lipoprotein metabolism.While much has been published on the structure-function relationship of LPL, little is known concerning the structural basis of HL action and secretion.Human HL is a glycoprotein and its predicted amino acid seque
Summary: Acute myeloid leukemia (AML) is caused by recurrent mutations in members of the gene regulatory and signaling machinery that control hematopoietic progenitor cell growth and differentiation.Here, we show that the transcription factor WT1 forms Pivot Tube a major node in the rewired mutation-specific gene regulatory networks of multiple AML
In the Catholic Pivot Tube areas of Europe, the human remains (both their bones and the fabrics they touched) of persons considered to have been exceptional are usually stored for transformation into relics.The production and the reproduction of the object-relic takes place within monasteries and is carried out firstly on the material level.In this
Most cells exchange ions and small metabolites via gap junction channels.These channels are made of two hemichannels (connexons), each formed by the radial arrangement of six connexin (Cx) proteins.Connexins span the bilayer four times (M1-M4) and have both amino- and carboxy-termini (NT, CT) at the cytoplasmic side of the membrane, forming two ext